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KMID : 1161520170210040241
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Animal Cells and Systems
2017 Volume.21 No. 4 p.241 ~ p.254
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Induction of telomere shortening and cellular apoptosis by sodium meta-arsenite in human cancer cell lines
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Kim Yoon-Dong
Jang Si-Jeong
Lim Eun-Ji
Ha Jeong-Sook
Shivakumar Sharath Belame
Jeong Gie-Joon
Rho Gyu-Jin
Jeon Byeong-Gyun
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Abstract
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The present study assessed the cytotoxicity of sodium meta-arsenite (SMA) on telomere shortening and cellular apoptosis in human A-549, MDA-MB-231 and U87-MG cancer cell lines. Following 2 weeks of 1?μM SMA treatment, population doubling time (PDT) was significantly (P?
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KEYWORD
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Human, cancer, sodium meta-arsenite, telomere length, apoptosis
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